groninger, ARaymondlife and SCHOTT team up to demonstrate flexible and agile aseptic manufacturing at CPhI worldwide

With ever more new pharmaceutical drug products entering the market, pharmaceutical companies are facing new challenges when it comes to fill and finish. These processes now need to adapt to different output speeds, changeover times or the ability to process nested containers i.e. syringes, cartridges or vials on one filling line. In particular, pharma companies in biotech or cell and gene therapy development as well as large pharma manufacturers with CMO activities are consequently in need of flexible approaches in fill and finish. One such approach will be demonstrated at this year’s CPhI Worldwide in Frankfurt, Nov. 5-7, by Groninger, ARaymondlife and SCHOTT at booth 111F10.

To meet the growing demand for more flexibility in aseptic manufacturing, the companies are bringing together adaptiQ® ready-to use (RTU) vials from SCHOTT, RayDyLyo® RTU plastic press fit caps from ARaymond, and the Nestfiller machine portfolio from groninger.

The pre-sterilized, nested adaptiQ® vials are part of the SCHOTT iQ® platform. This holistic concept standardizes RTU syringes, vials, and cartridges within a single tub format to run on the same filling line, minimizing changeover times. All the components listed can be filled and closed with the groninger Nestfiller portfolio from smaller outputs to high speed equipment.

The groninger Nestfillers are designed and built to handle all nested components by simply changing format parts and thereby significantly reducing the machinery needed. In the case of existing equipment, a retrofit from a syringe to nested vials or cartridges is possible by installing or exchanging a set of format parts.

While running nested vials, the de-nesting and final closing with an aluminum cap on separate equipment is still common, it yet adds complexity and investment costs to the process. With RayDyLyo® press fit caps this process is reduced to just one operation in nest. Furthermore, ARaymond’s product allows groninger to install press fit technology on new or existing equipment in the same way a new nested format is mounted on the machine, by exchanging the sorting parts on the filling machine.

The combination of ARaymond, groninger and SCHOTT products is designed to meet the needs of future fill and finish operations by providing maximum flexibility. Visitors to CPhI Worldwide can explore the concept at ARaymondlife’s booth 111H51, groninger’s booth 110C10 and at SCHOTT’s booth 111F10.

About groninger

groninger is one of the world's leading manufacturers of filling and sealing machines for the pharmaceutical, cosmetics and consumer healthcare industries. The slogan "We fill Visions with Life" aptly describes what groninger stands for: excellent know-how, innovative solutions and partnership-based cooperation in the special engineering sector. Since it was founded by Horst Groninger in 1980 the company has become a hidden champion and innovation leader in the industry. Today the company, managed by the family's second generation, employs around 1,300 people at its sites in Crailsheim, Schnelldorf and Charlotte (USA). The company headquarters are in Crailsheim.


SCHOTT is a leading international technology group in the areas of specialty glass, glass-ceramics and related high-tech materials. With over 130 years of experience, the company is an innovative partner to many industries, including the home appliance, pharma, electronics, optics, life sciences, automotive and aviation industries. SCHOTT has a global presence with production sites and sales offices in 34 countries. In the 2017/2018 fiscal year, the group generated sales of EUR 2.08 billion with over 15,500 employees. SCHOTT AG has its headquarters in Mainz (Germany) and is solely owned by the Carl Zeiss Foundation. This is one of the oldest private and largest science-promoting foundations in Germany. As a foundation company, SCHOTT assumes special responsibility for its employees, society and the environment.

About ARaymond

ARaymondlife is a company of ARaymond Network dedicated to the development of packaging solutions for the healthcare market. With more than 7,000 employees in 25 countries worldwide, the ARaymond Network designs, manufactures and markets fastening and assembly solutions for industry. Founded in 1865, this French family firm has always put people at the heart of its success. Guided by innovation and value creation, the ARaymond Network is one of the global leader in fastening and assembly solutions for the automotive market.

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